MSBase Foundation Directors

 

Helmut Butzkueven (Managing Director) MBBS, PhD, FRACP

Helmut Butzkueven is an academic neurologist specializing in management of Multiple Sclerosis (MS) and real-world MS outcomes research, including drug safety and long-term effectiveness studies.

He is the van Cleef Roet Professor and Head of the Department of Neuroscience,  Central Clinical School, Monash University, and Director of Neurology at the Alfred Hospital, all in Melbourne.

He is a current NHMRC Leadership Investigator.

Thomas P Leist, MD, PhD (Chair)

Prof Thomas P Leist MD PhD is Director of the Comprehensive Multiple Sclerosis Center at Jefferson University. He is involved in basic and clinical research into multiple sclerosis and the Neurology of autoimmune disorders and infections of the central nervous system. He has also conducted research on the Neurobiology and pathology of retroviral, herpetic, and bacterial infections and the role of lymphokines at the National Institute of Neurological Diseases and Stroke, the University of Miami, the University of California at Los Angeles, and the University of Zurich. A Prof Leist is the author of many research articles and is board-certified in Neurology

Lily Habib, BBus, MBA

Lily Habib has extensive experience in strategic planning, business development and growth, sale and acquisitions, portfolio management, sustainability strategy, audit, risk, financial and change management. Lily has 20 years of experience in the energy sector and previously led Pacific Hydro’s Australian generation and projects business, with development in wind, solar, hydro, hydrogen and storage, adding 2 GW large-scale development to the company’s project pipeline. Lily also managed the $3billion sale of Pacific Hydro in 2015. Lily holds an MBA, a Graduate Diploma in Applied Finance and Investment, and a Bachelor of Business (Applied Economics).

Paarami Udugama, LLB/BCom, GradDip Corporate Governance

Ms Paarami Udugama is currently a Group Counsel within the Legal Team at AGL Energy Limited. Prior to this role Paarami spent a number of years in private practice working at global professional services firm PricewaterhouseCoopers and at top-tier Australian law firms Herbert Smith Freehills (formerly Freehills) and King and Wood Mallesons (formerly Mallesons Stephen Jaques). Her extensive experience includes advising major ASX listed companies in the areas of corporate and commercial law, corporate governance, competition and consumer law.
Paarami graduated from Monash University with a Bachelor of Commerce and a Bachelor of Laws. She holds a Graduate Diploma in Applied Corporate Governance from the Governance Institute of Australia and is a Member of the Australian Institute of Company Directors.

 

Orla Gray, MD

Dr Orla Gray graduated in Medicine from Queens University Belfast in 1997. She became a member of the Royal College of Physicians in 2001. She completed her post-graduate neurology training in Northern Ireland. In 2006 she gained an MD for her research on the epidemiology, genetica and quality of life in MS. She perfomed a one year clinical and research fellowship in MS and Neurorehabilitation in the Royal Melbourne Hospital in 2008.

Dr Orla Gray currently works in the Ulster Hospital in Belfast as a Consultant Neurologist with a specialist interest in MS.

 

Scientific Leadership Group (SLG)

The MSBase Foundation has delegated responsibility for the oversight of the MSBase Registry research activities to a Scientific Leadership Group (SLG). All members, including the chairperson of the SLG, are chosen among neurologists, scientists and nurses with senior experience in the field of multiple sclerosis. 

According to the MSBase Constitution of 2013 the role of the SLG is as follows:

  • Provide scientific assistance to the Foundation with respect to the Foundation's database and website
  • Make recommendations to the Foundation with respect to financing of projects
  • Act as custodians of the data on the Foundation's database

The SLG is led by the Chair, A/Prof Tomas Kalincik. The SLG Regulations can be accessed here.

 

 

MSBase SLG Members 

 
 

  

Raed Alroughani, MD, FRCPC

Dr. Raed Alroughani is a consultant neurologist and the director of MS clinic at Amiri and Ibn Sina hospitals. He received his degree in medicine (MD) from Charles University (Czech Republic). He completed his neurology residency at the University of British Columbia and subsequently obtained the neurology certification from the Royal College of Physicians & Surgeon (Canada). He then completed a fellowship in Multiple Sclerosis at the University of British Columbia.

Dr Alroughani’s fields of interest are principally directed towards the epidemiology and therapeutics of MS. He established the national MS registry and the multi-disciplinary MS clinic in Kuwait. He authored and co-authored more than 150 publications. Dr Alroughani was awarded the National Prize for scientific production in the field of medical science in 2017 and the best researcher award by Amiri Hospital in 2018.

He is a founding member and the secretary general of MENACTRIMS. He sits on the executive boards of various scientific associations, steering committees, and advisory boards, mainly in the field of MS.

 

Ayse Altintas, MD

Prof.Ayse Altintas became a neurology specialist (Ege University) in 1992, “associate professor” in 1997, and “professor” in 2003 (Istanbul University, Cerrahpaşa Medical Faculty). Between 1991-1992, she studied neuroimmunology under the mentor of Prof. Moses Rodriguez at the Mayo Clinic and worked on the experimental model of Multiple Sclerosis (MS). With this work, she was awarded the Eczacıbaşı Medical Incentive Award. In 2001, she worked with Prof.C.Lucchinetti and Prof. B. Weinshenker on the neuroimmunopathological mechanisms, radiological correlations and demyelination / remyelination mechanisms of MS at Mayo Clinic.


She has been a Board member of the European Neuroimmunology School for many years, a member of the BioMS-eu working group, the coordinator of the Turkish Neurological Association’s Neuroimmunology working group, SLG member of MSBase and member of international scientific committee of Guthy Jackson Charitable Foundation. Her current works are focused on multiple sclerosis and neuromyelitis optica spectrum disorders and primarily aimed to clarify possible disease biomarkers and mechanisms at the immunopathological level by clinical and laboratory studies.
Prof.Ayse Altintas has been working at Koç University School of Medicine Neurology Department and Research Center for Translational Medicine(KUTTAM) since June 2018.

 

 

 

Helmut Butzkueven, (Managing Director) MBBS, PhD, FRACP

Helmut Butzkueven is an academic neurologist specializing in management of Multiple Sclerosis (MS) and real-world MS outcomes research, including drug safety and long-term effectiveness studies.

He is the van Cleef Roet Professor and Head of the Department of Neuroscience,  Central Clinical School, Monash University, and Director of Neurology at the Alfred Hospital, all in Melbourne.

He is a current NHMRC Leadership Investigator.

 

Edgardo Cristiano, MD

Board certified as a neurologist in 1995, Edgardo Cristiano earned his MD from the University of Buenos Aires, School of Medicine, where he now teaches. He is also currently Assistant Chief of the Neurology Department, and Chief of the Multiple Sclerosis Section at the Hospital Italiano de Buenos Aires.

He is a member of both the executive board and scientific committee of the Latin-American Committee for Treatment and Research in Multiple Sclerosis (LACTRIMS), and Director of Esclerosis Multiple Argentina (the national MS society). He represents Latin America on the Immunosuppressive Committee of the European Charcot Foundation. He is a member of Sociedad Neurologica Argentina (SNA) and of the World Federation of Neurology (WFN), and a corresponding fellow of the American Academy of Neurology (AAN).

Dr Cristiano was principal investigator of the Cop-1500 Study (1995-1996), the Coral Study GA 7023 (2000-2001), and the IM 101200 Study (ongoing).

 

 

 

 

Orla Gray, MD

Dr Orla Gray is a Consultant Neurologist who specializes in the management of Multiple Sclerosis, based in the South Eastern Health and Social Care Trust in Northern Ireland. During her neurology training, she gained an MD for her research on the Epidemiology, Genetics and Quality of Life in MS and performed a one year clinical and research fellowship in MS and Neurorehabilitation in the Royal Melbourne Hospital.

She became a member of the MSBase SLG in 2009 (chair 2012-2016) and is a member of the Research Sub-committee (chair 2014-2016). She is Co-Chair and Clinical Lead of the Pregnancy, Women’s Health and Neonatal Outcomes Sub-committee.

Her key research interests include Real World Outcomes in MS and Women’s health, including pregnancy in MS.

 

Dana Horakova, MD, PhD

Assoc. Prof. Dana Horakova, MD, PhD, completed medical school at Charles University in 1992. Since 1999, she has been working in the MS Centre, 1st Faculty of Medicine, Charles University, Prague. In 2006, she spent 6 months training at the BNAC, in Buffalo, USA.
In 2010, she received her PhD with a thesis titled “Predictive Markers for Clinical Development in Patients with MS.”
Dr. Horakova is a member of the Immunological Committee of Czech Neurological Society
She was the chair of the Scientific Leadership Group in the MSBase between 2014-6/2020
Her key research interests are - markers of disease activity and treatment response (clinical and MRI, especially implementation and validation of quantitative volumetric MRI techniques in a routine clinical practice), use of databases and registries in MS, and phenotype-genotype project.

 

 

 

 

Stella Hughes, MD

Dr Stella Hughes obtained her medical degree from Queen’s University Belfast (QUB) and undertook neurology training in Northern Ireland. She completed a research fellowship with the MSBase Registry in Melbourne in 2011. She was awarded an MD from QUB in 2014 for her thesis entitled ‘Epidemiological Perspectives on MS’. She works as a Consultant Neurologist with specialist interest in MS at the Belfast HSC Trust and is an Honorary Lecturer in Queen’s University, Belfast. She is a current member of the ECTRIMS Council and a member of the UK MS Pregnancy Register Steering Group.

 

 

Guillermo Izquierdo, MD

Dr Izquierdo became a Medical Doctor in 1975, and completed his studies in Neurology at the University of Málaga, Spain in 1982. After working in the fields of Neurology, Neuropsychology and Neuropathology at Pitié-Salpêtrière Hospital in Paris, Dr. Izquierdo returned to Spain. He was Professor of Medicine at the University of Seville and Head of the Multiple Sclerosis Unit, Neurology Service, at the Virgin Macarena University Hospital of Seville, Spain.
At present, Dr Izquierdo is Head of the Multiple Sclerosis Unit, Neurology Service, at Vithas Hospital of Seville, Spain.


Dr Izquierdo's research interests are in the fields of genetics and neuropsychology. In the last 5 years he has published over 100 articles in various peer-reviewed journals, and chapters on Multiple Sclerosis in several Spanish books for medical students, family doctors, nurses and neurology students.

Dr Izquierdo has been a member of ECTRIMS since 1999, and is ex-coordinator of the Spanish Multiple Sclerosis Group of the National Spanish Neurological Society (2000-2001).

 

 

 

 

 

Vilija Jokubaitis, PhD

Dr Jokubaitis completed a Bachelor of Commerce and Bachelor of Science double degree at the University of Melbourne, followed by a PhD in Molecular Neurobiology at the Florey Institute of Neuroscience and Mental Health/University of Melbourne. She is a Senior Research Fellow and Group Leader at Monash University in Melbourne, Australia. Her research focus lies in MS prognostics and treatment individualisation, with a particular focus on MS genetics, environment, and Women’s Health. Her research group actively engages with MSBase. She has led a number of MSBase publications, as well as a number of collaborative research projects both within and outside of MSBase. Vilija is the Co-Chair and Scientific Lead of the MSBase SLG Pregnancy, women’s health and neonatal outcomes sub-committee.

 

Tomas Kalincik, MD, PhD

Tomas Kalincik is a neurologist and statistician at the Royal Melbourne Hospital, and a Senior Research Fellow at the University of Melbourne. He holds a degree in medicine/surgery from Charles University in Prague, and has trained as an neurologist in the Czech Republic. He completed a PhD in neuroscience at the University of New South Wales and a Postgraduate Certificate of Biostatistics at the University of Melbourne.

Tomas is a member of the MSBase Scientific Leadership Group and the chair of the MSBase Data Quality Committee. Together with his research team, he is an active participant in the global MSBase collaboration. Tomas has led a number of MSBase publications and leads several collaborative projects within as well as outside the MSBase network. His main research interests span treatment outcomes in MS, individualised therapy, prognostics, epidemiology and the utility of volumetric MRI in MS.

 

 

 

Jens Kuhle, MD, PhD

Dr Jens Kuhle obtained his MD from the Eberhard-Karls University in Tübingen, Germany and went on to specialise in neurology and neuroimmunology at the University Hospital Basel. He is the Head of the MS Centre at the University Hospital Basel, deputy Head of the Research Center for Clinical Neuroimmunology and Neuroscience Basel and the Principal Investigator of the Swiss MS Cohort Study. His main research interests include bodyfluid biomarkers and observational cohort studies in MS.

 

Thomas P Leist, MD, PhD

Prof Thomas P Leist MD PhD is Director of the Comprehensive Multiple Sclerosis Center at Jefferson University. He is involved in basic and clinical research into multiple sclerosis and the Neurology of autoimmune disorders and infections of the central nervous system. He has also conducted research on the Neurobiology and pathology of retroviral, herpetic, and bacterial infections and the role of lymphokines at the National Institute of Neurological Diseases and Stroke, the University of Miami, the University of California at Los Angeles, and the University of Zurich. A Prof Leist is the author of many research articles and is board-certified in Neurology

 

Sara Eichau Madueno, MD

Sara Eichau was born in Seville, Spain in 1984. She completed her degree in Medicine and Surgery in 2008 at the University of Seville and her residency in Neurology also in Seville at Virgen Macarena Hospital in 2013.
She is currently working as a Neurologist focusing on Multiple Sclerosis at the MS Unit at Virgen Macarena Hospital (Dr. Izquierdo´s site), and as a Treating Neurologist in more than 30 clinical trials in MS. Sara is interested in familial and progressive forms of MS, new biological and stem cell therapies for MS and she is involved in several projects analyzing the efficacy, tolerability and safety of MS treatments.

 

 

Jiwon Oh, MD, PhD, FRCPC

Jiwon Oh is a staff neurologist, scientist, and Medical Director of the Barlo Multiple Sclerosis (MS) Program at St. Michael’s Hospital, University of Toronto and specializes in the care of people living with MS. Dr. Oh’s research focuses on developing advanced MRI techniques in the spinal cord and brain for use in clinical settings. She leads the MRI research program at St. Michael’s Hospital, and is the principal investigator on numerous local multi-center collaborative studies, including the Canadian Prospective Cohort Study to Understand Progression in MS (CanProCo), which is a national prospective cohort study designed to better understand progression in MS. Dr. Oh is also the Secretary and an Executive Committee member of the North American Imaging in MS Cooperative (NAIMS) representing a multi-national collaborative MRI research endeavor in MS with over 30 sites in North America.

 

 

Liliana Patrucco, MD

Dr Patrucco received her medical degree in 1989 from the University of Buenos Aires, Argentina, and her neurological certification in 2000, when she also joined the Department of Neurology as a staff physician at Hospital Italiano de Buenos Aires. Liliana is now Co-Director of the Multiple Sclerosis Centre and the Neurology Residence Tutor at the same hospital, as well as Assistant Professor of Neurology at the University of Buenos Aires, and a member of LACTRIMS. Dr Patrucco’s interests lie in the fields of epidemiology, genetics and clinical aspects of multiple sclerosis, which have been the subject of several published papers by Liliana.

 

Alessio Signori, PhD

Alessio Signori is currently Assistant Professor in Medical Statistics at University of Genoa, Italy. He works in Multiple Sclerosis (MS) field from 10 years. He obtained the PhD in Biostatistics in 2013 and was post-doc in the same field up to 2018 under the supervision of Prof. Maria Pia Sormani. In 2011 he was visiting fellow at Neurological Centre of McGill University in Montreal under the supervision of Prof. Douglas Arnold. In 2015 he was recipient of the MSBase Fellowship. He was speaker at EAN, ECTRIMS and Charcot congress. He is interested mainly on the methodological aspects of research projects on MS patients. He is author or coauthor of more than 150 papers on international journals.

 

 

Anneke van der Walt, MD

A/Prof Anneke van der Walt is a Neurologist specializing in the management of Multiple Sclerosis and Neuro-ophthalmology. She is appointed as the Director, MS and Neuroimmunology and is the Head of Neuro-ophthalmology at Alfred Health, Melbourne, Australia. She leads the MS and Neuroophthalmology research group in the Department of Neuroscience, Central Clinical School, Monash University.

Her research interests include digital biomarkers and applied technology, real-world data, MS cognition and cerebellar function. She has a keen interest in Women’s Health in MS as well as symptom management in people with MS.

 

Oliver Gerlach, MD, PhD

Dr. O. Gerlach, MD, PhD, studied medicine at the Maastricht University in the Netherlands and graduated in 2005. In 2006, he started his training in Neurology at the Maastricht University Medical Centre+ and finished this May 2012. Since then he works as a neurologist at the Zuyderland Medical Centre in the Netherlands. O. Gerlach is chairman of the department of Neurology. He participates as a neurologist at the academic MS Centre Limburg at Zuyderland Medical Centre and is involved in MS related research.